Estimation of the Iron Absorption from Ferrous Glycinate-loaded Solid Lipid Nanoparticles by Rat Everted Intestinal Sac Model
نویسندگان
چکیده
منابع مشابه
A novel approach to oral iron delivery using ferrous sulphate loaded solid lipid nanoparticles.
Iron (Fe) loaded solid lipid nanoparticles (SLN's) were formulated using stearic acid and iron absorption was evaluated in vitro using the cell line Caco-2 with intracellular ferritin formation as a marker of iron absorption. Iron loading was optimised at 1% Fe (w/w) lipid since an inverse relation was observed between initial iron concentration and SLN iron incorporation efficiency. Chitosan (...
متن کاملNovel sulpiride-loaded solid lipid nanoparticles with enhanced intestinal permeability
BACKGROUND Solid lipid nanoparticles (SLN), novel drug delivery carriers, can be utilized in enhancing both intestinal permeability and dissolution of poorly absorbed drugs. The aim of this work was to enhance the intestinal permeability of sulpiride by loading into SLN. METHODS A unique ultrasonic melt-emulsification method with minimum stress conditions was used for the preparation of SLN. ...
متن کاملcontrol of the optical properties of nanoparticles by laser fields
در این پایان نامه، درهمتنیدگی بین یک سیستم نقطه کوانتومی دوگانه(مولکول نقطه کوانتومی) و میدان مورد مطالعه قرار گرفته است. از آنتروپی ون نیومن به عنوان ابزاری برای بررسی درهمتنیدگی بین اتم و میدان استفاده شده و تاثیر پارامترهای مختلف، نظیر تونل زنی(که توسط تغییر ولتاژ ایجاد می شود)، شدت میدان و نسبت دو گسیل خودبخودی بر رفتار درجه درهمتنیدگی سیستم بررسی شده اشت.با تغییر هر یک از این پارامترها، در...
15 صفحه اولAn Investigation into the Role of P-Glycoprotein in the Intestinal Absorption of Repaglinide: Assessed by Everted Gut Sac and Caco-2 Cell Line
The present study aimed at exploring the potential of the P-glycoprotein (P-gp) transporters as a barrier to the repaglinide (REG) epithelial permeability. In-vitro intestinal absorption models, the everted gut sac, and Caco-2 cell line, were used to study the possible role of P-gp in intestinal transport of REG. In the everted gut sacs, apparent permeability coefficients showed cargo concentra...
متن کاملCytotoxicity of Tamoxifen-Loaded Solid Lipid Nanoparticles
Breast cancer is one the most important health concerns of the modern society (Ferlay et al., 2007). Worldwide, it is estimated that over one million new cases of breast cancer are diagnosed every year, and more than 400 thousands will die from the breast cancer (Coughlin & Ekwueme, 2009) The life-time risk in women contracting breast cancers is estimated to be 1 in 8, which is the highest amon...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Food Science and Technology Research
سال: 2017
ISSN: 1344-6606,1881-3984
DOI: 10.3136/fstr.23.567